FEX allows you to run x86 and x86-64 binaries on an AArch64 host, similar to qemu-user and box86. It has native support for a rootfs overlay, so you don't need to chroot, as well as some thunklibs so it can forward things like GL to the host. FEX presents a Linux 5.15+ interface to the guest, and supports only AArch64 as a host. FEX is very much work in progress, so expect things to change.