UltraStyle is another Frontend designed for arcade cabinets but works just as well on your desktop PC. I really like the GUI on this one. It's quite unique. Setup isn't as easy as some and is a bit time consuming, but the end results are well worth it. Be sure to read the documentation.
Does not work with newer version of MAME, Update back in February 2007 stated the problem would be fixed soon??
Download the Hotfix for compatibility with newer versions of MAME.